星期四, 10月 15, 2009

Endocrine review

Hypercalcemia


Malignancy,


PTHrP or humoral factor( IL1, IL16)


Dog, Lymphoma, apocrine gland adenocarcinoma,


thymoma,




Vitsmin D toxicity, 25-OH-D


cholecalciferol rodenticide ingestion=> vit D2 slow clear resulting in persisitent hypercalcemia


anti psoriatic cream




Idiopathic,


cat, especailly long hair, Initially no clinical signs, progress to calium oxalate stones,


Some have CRF, no acid/base, no PT tumor,


elevated iCa decrease PTH, Dietary based...




Hypercalcemia


Face itch, self mutilation,






  • Primary hypothyroidism


  • uncommon.


Iatrogenic,





TREATMENT,



Ca+ VIt D,



Calcitriol is the best choice, with low halflife, but expensive, 300 /month



Eclampsia





  • first three week post partum.


  • respiratory alkalosis lead to hypo calcemia.


2nd



Nutritional. excessive phosphate and inadequate calcium resorbtion and ospenia recommend 1:1 for cat and 1:2 for dogs.



vitd deficiency lead to inadequate of calcitriol rubber jaw syndrome.



Acromegaly cat diabetes. bigger head and skull and paw.



dwarfism.



Endocrine tumor, insulinoma, gastrinoma, and



hypogycemia, DDx liver disease.


Diabetes insipidus,


response to ADH, central.


alopecia and enlarged vulva, lethargy. muscle atrophy.


Insulinoma, ferret has more pancrease thatn any other species.


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